Aug 2024 - Present | New Delhi, India
Project Associate-I, INGEN-HOPE Lab
CSIR - Institute of Genomics and Integrative Biology
PI: Dr. Rajesh Pandey
- Executed end-to-end Oxford Nanopore dengue surveillance pipelines across longitudinal clinical cohorts.
- Developed Maxscriber, a Linux CLI tool for clinical metadata transcription, patient stratification, QC validation, and statistical visualization.
- Performed haplotype-resolved CpG methylation analysis on long-read human WGS data using Modkit.
- Leading SNP-based genomic characterization of ESKAPE pathogens from ONT data across active collaborations.
Dec 2024 - May 2025 | Karaikudi, India
M.Sc. Dissertation: Multi-Epitope Vaccine Design Against Hepatitis B Virus
Alagappa University
Supervisor: Dr. M. Karthikeyan
- Screened more than 111,000 HBV protein sequences across 8 genotypes for conservation, antigenicity, and human non-homology.
- Built and validated a multi-epitope construct with greater than 97% global population coverage for MHC-I/II binding.
- Automated more than 2,000 immuno-toxicity filtering steps using custom Perl scripts.
- Modeled host immune response using C-ImmSim and codon-optimized the final construct for expression in E. coli.
May 2024 - Jul 2024 | Chandigarh, India
Research Intern
CSIR - Institute of Microbial Technology
Supervisor: Dr. Srikrishna Subramanian
- Benchmarked five prokaryotic genome annotation pipelines on Thermodesulfobium narugense.
- Identified a Signal Peptidase II gene absent from NCBI-PGAP annotation and validated it using AlphaFold3 and DALI.
- Supported functional assignment with PSAURON scoring and DIAMOND-Blastp domain mapping.
