CSIR-IGIB
ONT Dengue Genomic Surveillance
End-to-end analysis of Oxford Nanopore dengue sequencing data across longitudinal clinical cohorts, integrating basecalling, alignment, variant calling, ARTIC workflows, and downstream cohort interpretation.
Projects
Selected research and software projects across long-read sequencing, clinical cohort informatics, host-pathogen genomics, microbial annotation, and immunoinformatics.
Clinical metadata automation
Maxscriber
Linux CLI tool automating clinical metadata transcription, patient stratification, QC validation, and statistical visualization for ONT dengue surveillance projects.
Epigenomics
Haplotype-Resolved Methylation Profiling
Long-read human whole-genome sequencing workflow using Modkit for phased CpG methylation analysis, differential methylation profiling, and gene-level epigenetic annotation.
Pathogen genomics
ESKAPE Genomic Characterization
Ongoing SNP-based characterization of ESKAPE pathogens from ONT data across national and international collaborative infectious disease projects.
M.Sc. dissertation
HBV Multi-Epitope Vaccine Design
Reverse vaccinology workflow that screened more than 111,000 HBV protein sequences across 8 genotypes and produced a structurally validated multi-epitope construct.
CSIR-IMTECH
Microbial Genome Annotation Benchmarking
Comparative benchmarking of five prokaryotic annotation pipelines on Thermodesulfobium narugense, including structure-assisted validation of a missed Signal Peptidase II gene.
Patent
Indian Patent No. 520964 covers an apparatus for collecting tree sap, designed around reducing Nipah virus transmission risk.
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